DISTRIBUTION, BIOLOGICAL ACTIVITIES, SYNTHESIS, AND PURIFICATION METHODS FOR PODOPHYLLOTOXIN AND ITS DERIVATIVES
نویسندگان
چکیده
منابع مشابه
Biological activities of isatin and its derivatives.
Isatin is an endogenous compound identified in humans that possesses a wide range of biological activities. Isatin has anxiogenic, sedative, anticonvulsant activities and acts as a potent antagonist on atrial natriuretic peptide receptors in vitro. A series of p-substituted isatin semicarbazones have shown anticonvulsant activity in MES, scPTZ and scSTY tests. Various isatin-N-Mannich bases of ...
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A series of novel (arylimino-2-oxo-2,3-dihydro-indol-1-yl)-acetic acid N'-(4-aryl-2-yl)-hydrazide derivatives (5a-g) were synthesized. The structures of the newly synthesized compounds were characterized by elemental analysis, FT-IR, H-, C-NMR and mass spectroscopy. The compounds were screened in vitro for antibacterial and antifungal activities against some human pathogenic microorganisms by t...
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ژورنال
عنوان ژورنال: Química Nova
سال: 2014
ISSN: 0100-4042
DOI: 10.5935/0100-4042.20140294